The Role of M2 Pyruvate Kinase in the Screening of Bowel Inflammation

Ruswhandi -, Marcellus Simadibrata, Irsan Hasan


Background: This is a study to determine if M2 Pyruvate Kinase (M2-PK) can be used to screen the presence of bowel inflammation.

Method: The study design being used is diagnostic test. In this study, we recruited 76 participants and performed colonoscopy examination as a gold standard and faecal M2-PK as the examined procedure.

Results: From the result of this study, we identified the important role of M2-PK to screen the presence of bowel inflammation with the cut-off point of 1.05 U/mL compared to colonoscopy as gold standard with the sensitivity of 86.2%, specificity 81.8%, positive predictive value 96.6%, and negative predictive value 50%.

Conclusion: From the result of this study, we suggested M2-PK examination to screen bowel inflammation in patients with lower gastrointestinal tract problems.



M2 Pyruvate kinase; colonoscopy; screening; intestinal inflammation

Full Text:




  • There are currently no refbacks.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License