Propofol Sedation in Diagnostic Upper Gastrointestinal Endoscopy

Christophorus Simadibrata, Benvenuto Axel, Syahrizal Syahrizal, Dina Ikawari, Paulus Simadibrata, Marcellus Simadibrata


Background: Sedation are commonly used these days in patients that having gastrointestinal endoscopy. Propofol is sedative  agent  that  commonly  used  in  endoscopy procedure.

Method: All   patients   who   were   performed   diagnostic   EGD   in   Abdi   Waluyo   Hospital’s Gastrointestinal Endoscopy Unit from January 1st   2017 – 31st   December 2017, included in this study. The amount of Propofol, duration during hypnosis/sedation and adverse effects were all recorded.

Results: 170  patients  were  performed  diagnostic  EGD  with  Propofol  sedation,  most  of them were male (87 patients, 51,5%). The median age was 48,78 + 14. The median Body Mass Index  (BMI)  was  24.45.  The median of duration of hynosis (sedation) during EGD was 5 minutes. The median of propofol total dose during EGD was 180 mg. Adverse effects that found during Propofol sedation are muscle twitching(10.6% patients) and pain in area of  injection(80% patients). 

Conclusion: The duration of propofol hypnosis/sedation during Esophagogastroduodenoscopy examination was 5 minutes. Propofol total dose needed for diagnostic EGD was 180 mg. The common adverse effects of propofol are muscle twitching and pain in area of injection.


Propofol; endoscopic sedation; adverse effect

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