A Rare Case Of Acute Pancreatitis Cause by Newly Diagnosed Graves’ Disease: A Successful Therapeutic Option

Authors

  • Azzaki Abubakar Gastroenterohepatology Division, Department of Internal Medicine, Faculty of Medicine, Syiah Kuala University, Banda Aceh, Aceh, 23111, Indonesia / Gastroenterohepatology Division, Departemen of Interna Medicine, General Hospital dr. Zainoel Abidin, Banda Aceh, Aceh, 23111, Indonesia
  • Fauzi Yusuf Gastroenterohepatology Division, Department of Internal Medicine, Faculty of Medicine, Syiah Kuala University, Banda Aceh, Aceh, 23111, Indonesia / Gastroenterohepatology Division, Departemen of Interna Medicine, General Hospital dr. Zainoel Abidin, Banda Aceh, Aceh, 23111, Indonesia
  • Desi Maghfirah Gastroenterohepatology Division, Department of Internal Medicine, Faculty of Medicine, Syiah Kuala University, Banda Aceh, Aceh, 23111, Indonesia / Gastroenterohepatology Division, Departemen of Interna Medicine, General Hospital dr. Zainoel Abidin, Banda Aceh, Aceh, 23111, Indonesia
  • Andrie Gunawan Gastroenterohepatology Division, Department of Internal Medicine, Faculty of Medicine, Syiah Kuala University, Banda Aceh, Aceh, 23111, Indonesia / Gastroenterohepatology Division, Departemen of Interna Medicine, General Hospital dr. Zainoel Abidin, Banda Aceh, Aceh, 23111, Indonesia
  • Hendra Zufry Endocrin, Metabolic and Diabetes Division, Departemen of Interna Medicine, General Hospital dr. Zainoel Abidin, Banda Aceh, Aceh, 23111, Indonesia
  • Meutia Nailan Edward School of Medicine, Department of Internal Medicine, Syiah Kuala University, Banda Aceh, Aceh, 23111, Indonesia
  • Khek Yu Ho Department of Medicine, National University of Singapore, Singapore

DOI:

https://doi.org/10.24871/2622025195-200

Keywords:

Acute pancreatitis, graves’ disease, hyperthyroidism

Abstract

Acute pancreatitis is a frequent disorder whose severity level varies from mild to life-threatening. This condition is characterized by abrupt inflammation of the pancreas. A 53-year-old male was having upper right abdominal pain and epigastric pain which began four hours after hospitalization. This case highlights the complexities of managing acute pancreatitis in a patient with Graves' disease, where hyperthyroidism may worsen pancreatitis and vice versa. Graves' disease is an autoimmune disorder causing hyperthyroidism, which can complicate pancreatitis management, particularly when treated with methimazole, which has been associated with acute pancreatitis. This case suggests a potential link between untreated Graves' disease and idiopathic acute pancreatitis. In patients presenting with unexplained pancreatitis, evaluation for hyperthyroidism may be warranted. The novelty of this case lies in the exclusion of all conventional etiologies and the possible role of autoimmune thyroid disease in pancreatic inflammation.

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Published

2025-08-15

How to Cite

Abubakar, A., Yusuf, F., Maghfirah, D., Gunawan, A., Zufry, H., Edward, M. N., & Ho, K. Y. (2025). A Rare Case Of Acute Pancreatitis Cause by Newly Diagnosed Graves’ Disease: A Successful Therapeutic Option. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 26(2), 195–200. https://doi.org/10.24871/2622025195-200

Issue

Vol. 26 No. 2 (2025): VOLUME 26, NUMBER 2, August, 2025

Section

Case Reports

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