Signet-Ring Cell Carcinoma of the Ampulla of Vater

Authors

  • Lianda Siregar Department of Gastroenterology and Hepatology, Dharmais National Cancer Center Hospital, Jakarta, Indonesia
  • Imelda M Loho Department of Gastroenterology and Hepatology, Dharmais National Cancer Center Hospital, Jakarta, Indonesia
  • Agus Sudiro Waspodo Department of Gastroenterology and Hepatology, Dharmais National Cancer Center Hospital, Jakarta, Indonesia
  • Dwi Sri Rejeki Department of Anatomical Pathology, Dharmais National Cancer Center Hospital, Jakarta, Indonesia
  • Fajar Firsyada Department of Surgery, Dharmais National Cancer Center Hospital, Jakarta, Indonesia
  • Rahmanandika Swadari Department of Gastroenterology and Hepatology, Dharmais National Cancer Center Hospital, Jakarta, Indonesia
  • Getty Inash Nandika Department of Gastroenterology and Hepatology, Dharmais National Cancer Center Hospital, Jakarta, Indonesia
  • Muhammad Iqbal Siregar Department of Gastroenterology and Hepatology, Dharmais National Cancer Center Hospital, Jakarta, Indonesia

DOI:

https://doi.org/10.24871/1922018126-129

Keywords:

Signet ring cell carcinoma, ampulla of Vater, pylorus-preserving Whipple procedure

Abstract

Signet-ring cell carcinoma (SRCC) of the ampulla of Vater is a very rare case and only 28 cases have beed reported in the English literature. Herein, we report a 59-year-old woman with SRCC of the ampulla of Vater. She developed symptoms of obstructive jaundice at early stage of disease and underwent pylorus-preserving Whipple procedure as definitive treatment. Histopathology examination showed numerous tumor cells with intracytoplasmic mucin and eccentric nuclei. Her tumor has already invaded the serosa of duodenum, but no infiltration to the stomach, pancreas, and lymphovascular structure. Her surgical margins and regional lymph nodes were free of tumor. She was diagnosed with T2N0M0 (stage IB) SRCC of the ampulla of Vater. No adjuvant treatment was given and she has been doing well for five months after surgery.

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Published

2020-07-21

How to Cite

Siregar, L., Loho, I. M., Waspodo, A. S., Rejeki, D. S., Firsyada, F., Swadari, R., … Siregar, M. I. (2020). Signet-Ring Cell Carcinoma of the Ampulla of Vater. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 19(2), 126–129. https://doi.org/10.24871/1922018126-129

Issue

Vol. 19 No. 2 (2018): VOLUME 19, NUMBER 2, August 2018

Section

Case Reports

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