Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria

Authors

  • Muhammad Vitanata Arfijanto Division of Tropical Infectious Disease, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya
  • Mohammad Imam Wahyudi Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Hospital, Surabaya https://orcid.org/0000-0002-9532-3173

DOI:

https://doi.org/10.24871/2422023172-175

Keywords:

malaria hepatopathy, jaundice, severe malaria, falciparum malaria

Abstract

Jaundice commonly occurs in severe malaria, seen in approximately 2,5% patients with falciparum malaria infection. Jaundice in malaria can be caused by intravascular hemolysis, disseminated intravascular coagulation (DIC) or malaria-related liver disorders. Malaria hepatopathy is a term that is often used to describe hepatocytic dysfunction in severe malaria, although inflammation does not occur in the liver parenchyma.  Malaria hepatopathy also characterized by a rise in serum bilirubin along with the rise in serum glutamate pyruvate trasnaminase levels. This two condition are similar but must be distinguished because of different treatment required.

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Published

2023-11-24

How to Cite

Arfijanto, M. V., & Wahyudi, M. I. (2023). Malaria Hepatopathy and Thrombocytopenia in Severe Falciparum Malaria. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 24(2), 172–175. https://doi.org/10.24871/2422023172-175