The Evolution of Double Pylorus Associated With NSAIDs-Induced Gastric Ulcer

Rasco Sandy Sihombing(1), Taolin Agustinus(2), Ari Fahrial Syam(3),


(1) Internal Medicine Division, Mgr Gabriel Manek SVD General Hospital, Atambua, East Nusa Tenggara
(2) Internal Medicine Division, Mgr Gabriel Manek SVD General Hospital, Atambua, East Nusa Tenggara
(3) Division of Gastroenterology, Pancreatobiliary and Digestive Endoscopy, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia / Cipto Mangunkusumo General National Hospital, Jakarta, Indonesia
Corresponding Author

Abstract


Double pylorus is an uncommon condition where two communicating channels between the gastric antrum and duodenal bulb exist and found incidentally by esophagogastroduodenoscopy. This case report presented a 77-year old Timorese man with long-term frequent use of nonsteroidal anti-inflammatory drugs (NSAIDs) who came to hospital because of hematemesis and melena. The initial endoscopy showed gastric ulcer and the double pylorus. Nine months later, the double pylorus structure fused into one large opening. This elderly patient with a history of NSAIDs abuse was diagnosed with acquired double pylorus due to a gastric ulcer complication. The fusion of the two channels occurred as a result of septum destruction, likely caused by fistulous tract ulceration or mechanical damage from food bolus. This structure predisposes the patient to bile regurgitation and ulcer recurrence, emphasizing the need for continued monitoring and avoidance of ulcerogenic factors.

Keywords : double pylorus, gastroduodenal fistula, NSAIDs, gastric ulcer, follow-up


Keywords


Double pylorus, gastroduodenal fistula, NSAIDs, gastric ulcer, follow-up

References


Lee BC, Jasmi AY. Double pylorus. Med J Malaysia 2003;58:440-2.

Deshmukh F, Devani K, Francisco P, Merrell N. Gastroduodenal fistula: a rare finding with an atypical presentation. Gastroenterology Res 2020;13, 121–4.

Oktaricha H, Miftahussurur M. Double pylorus in upper gastrointestinal bleeding. Case Rep Gastroenterol 2021;15:332–7.

Gala D, Dhir BS, Desai J, Rammohan R, Jiyani R, Yeroushalmi K, et al. Acquired idiopathic double pylorus: a rare endoscopic finding presenting with chronic anemia. Am J Gastroenterol. 2023;118(10S):S2664.

Laabidi S, Ben Mohamed A, Khsiba A, Yakoubi M, Mahmoudi M, Medhioub M, et al. Acquired double pylorus presenting as a gastrointestinal bleeding. Clin Case Rep 2022;10:e05634.

Lei JJ, Zhou L, Liu Q, Xu CF. Acquired double pylorus: clinical and endoscopic characteristics and four-year follow-up observations. World J Gastroenterol 2016;22:2153–8.

Fousekis F, Aggeli P, Kotsaftis P, Pappas-Gogos G. Double pylorus: report of a case with endoscopic follow-up and review of the literature. Gastroenterology Res 2018;11:154–6.

Naidoo R, Singh B. Congenital double pylorus. Case Rep Gastrointest Med. 2012;2012:537697.

Sansone N, Schnall HA, Somnay K. Evolution of the pylorus from a double to a triple lumen. Gastrointest Endosc 2009;69:949–50.

Hu TH, Tsai TL, Hsu CC, Lu SN, Hsio M, Changchien CS. Clinical characteristics of double pylorus. Gastrointest Endosc 54, 464–470 (2001).

Yuan C, Liu F, Xi CH, Pu K, Yang G, Wang XF, et al. Acquired double pylorus secondary to a completely epithelialized gastroduodenal fistula. Endoscopy. 2024;56:E884–5.

Chua C, Singh H, Patel P, Samuel S. A rare case of double pylorus in an elderly woman. Am J Gastroenterol. 2023;118(10S):S2024-S2025.

Hattori A, Kawabata H, Umeda Y, Tsuboi J, Yamada R, Hamada Y, et al. Adult hypertrophic pyloric stenosis that improved by spontaneous double channel pylorus formation. JGH Open. 2021;5:317–9.

Sufian S, Ominsky S, Matsumoto T. Congenital double pylorus : a case report and review of the literature. Gastroenterology 1977;73:154–7.

Graham SM, Lin F, Flowers JL. Symptomatic double-channel pylorus : successful treatment with a biliary sphincterotome. Surg Endosc 1994;8:792-3.

Miranda L, Nemeth K, Rivas J. S4297: Acquired double pylorus: A rare endoscopic finding of severe peptic ulcer disease. Am J Gastroenterol. 2023;118(10S):S2709.

Seyyedmajidi M, Shajari R, Vafaeimanesh J. An interesting finding in upper gastrointestinal endoscopy. Middle East J Dig Dis 2020;12:130–2.

Chiu HH, Chen CM, Mo LR. Evolution of Acquired Double Pylorus:A Case Report. J Intern Med Taiwan 2004; 15: 130-3

Safatle-Ribeiro AV, Júnior UR, Habr-Gama A, Gama-Rodrigues JJ. Double pylorus: case report and review of the literature. Rev Hosp Clin Fac Med Sao Paulo. 1999;54(4):131-4.


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DOI: 10.24871/261202593-97

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