The Role of Wisteria Floribunda (M2BPGi) Serum Level for Diagnosing Liver Fibrosis in Hepatitis B Patient: An Evidence Based Case Report

Authors

  • Yosafat Lambang Prasetyadi Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta
  • Agnes Elsha Maria Simbolon Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta
  • Anggi Anggelina Permatasari Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta
  • Dela Ryana Swaraghani Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta
  • Shafira Chairunisa Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta
  • Juferdy Kurniawan Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Dr. Cipto Mangunkusumo General National Hospital, Jakarta

DOI:

https://doi.org/10.24871/2022019129-133

Keywords:

Hepatits B, Fibrosis, M2BPGi, wisteria floribunda, liver biopsy

Abstract

Aim: To assess M2BPGi serum performance compared to liver biopsy in diagnosisng liver fibrosis

Method: Literature search using Pubmed®, Ebsco®, ProQuest®, Scopus®, Clinical Key databases, and the Cochrane Library® yield four relevant and full-text articles. The four articles were critically appraised for its validity, importance, and applicability.

Results: Sensitivity and specificity in all four studies showed that M2BPGi serum was inadequate to ruling in and ruling out the diagnosis of liver fibrosis in chronic hepatitis B patients. The difference in M2BPGi cut-off value to determine the stage of fibrosis in each study makes this value cannot be used as an accurate standard to determine the advanced stage (F≥3) of liver fibrosis. On the other hand, M2BPGi serum combined with other tests are known to improve the diagnostic accuracy.

Conclusion: MBP2Gi serum cannot be used as a diagnostic modality for detecting liver fibrosis in chronic hepatitis B patients.

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Published

2020-07-23

How to Cite

Prasetyadi, Y. L., Simbolon, A. E. M., Permatasari, A. A., Swaraghani, D. R., Chairunisa, S., & Kurniawan, J. (2020). The Role of Wisteria Floribunda (M2BPGi) Serum Level for Diagnosing Liver Fibrosis in Hepatitis B Patient: An Evidence Based Case Report. The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy, 20(2), 129–133. https://doi.org/10.24871/2022019129-133

Issue

Vol. 20 No. 2 (2019): VOLUME 20, NUMBER 2, August 2019

Section

Case Reports

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