Potential of Fecal-Oral Transmission and Gastrointestinal Manifestation of COVID-19

Randy Adiwinata(1), Visakha Revina Irawan(2), Jonathan Arifputra(3), Bradley Jimmy Waleleng(4), Fandy Gosal(5), Luciana Rotty(6), Jeanne Winarta(7),


(1) Department of Internal Medicine, Faculty of Medicine, Universitas Sam Ratulangi/Prof. dr. R. D. Kandou Hospital, Manado
(2) Department of Internal Medicine, Faculty of Medicine, Universitas Sam Ratulangi/Prof. dr. R. D. Kandou Hospital, Manado
(3) Department of Internal Medicine, Faculty of Medicine, Universitas Sam Ratulangi/Prof. dr. R. D. Kandou Hospital, Manado
(4) Division of Gastroenterology-Hepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Sam Ratulangi/Prof. dr. R. D. Kandou Hospital, Manado
(5) Division of Gastroenterology-Hepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Sam Ratulangi/Prof. dr. R. D. Kandou Hospital, Manado
(6) Division of Gastroenterology-Hepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Sam Ratulangi/Prof. dr. R. D. Kandou Hospital, Manado
(7) Division of Gastroenterology-Hepatology, Department of Internal Medicine, Faculty of Medicine, Universitas Sam Ratulangi/Prof. dr. R. D. Kandou Hospital, Manado
Corresponding Author

Abstract


The World Health Organization have declared COVID-19 as a pandemic. The COVID-19, caused by SARS-CoV-2, is spreading at an alarming rate and creates a significant worldwide burden to the economy while increasing morbidity and mortality. While COVID-19 was primarily considered as a respiratory-infection disease, several reports have shown that many COVID-19 infected patients have presented or developed some digestive symptoms. Many studies also demonstrated, using reverse transcriptase-polymerase chain reaction method, that SARS-CoV-2 are present in stools or other gastrointestinal tract secretions. All these reports raised the possibility of COVID-19 transmission via the fecal-oral route and the involvement of the gastrointestinal-liver system. Until further studies are available, physicians should be aware of the digestive manifestation of COVID-19 and use universal precautions to avoid the transmission of COVID-19 via the fecal-oral route.


Keywords


COVID-19; Coronavirus; gastrointestinal; liver; pandemic; infection

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DOI: 10.24871/211202053-58

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