Metastatic Cervical Cancer Presenting as a Sessile Polyp in the Ascending Colon

Imelda Maria Loho(1), Lianda Siregar(2), Dewi Iriani(3), Tiyas Hasnaa Faatinah(4),

(1) Department of Gastroentero-Hepatology, Dharmais Hospital, Indonesian National Cancer Center, Jakarta
(2) Department of Gastroentero-Hepatology, Dharmais Hospital, Indonesian National Cancer Center, Jakarta
(3) Department of Anatomical Pathology, Dharmais Hospital, Indonesian National Cancer Center, Jakarta
(4) Department of Gastroentero-Hepatology, Dharmais Hospital, Indonesian National Cancer Center, Jakarta
Corresponding Author


Patients with metastatic cervical cancer, particularly hematogenous metastasis, have a worse prognosis compared to those with localized cervical cancer. Gastrointestinal involvement of cervical cancer occurs in approximately 8% of cases and most lesions are located in the recto-sigmoid area due to direct extension of the disease. Here, we present a case of cervical adenocarcinoma spreading to the ascending colon as a sessile polyp and mimicking a hyperplastic polyp. Histopathological evaluation followed by immunohistochemistry analysis is needed to confirm the diagnosis.


cervical cancer; metastasi; sessile polyp; colon


Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, et al. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. Lancet Glob Health. 2020;8(2):e191-e203.

Yin Z, Tang H, Li L, Ni J, Yuan S, Lou H, et al. Impact of sites versus number of metastases on survival of patients with organ metastasis from newly diagnosed cervical cancer. Cancer Manag Res. 2019;11:7759-66.

Liu X, Meng Q, Wang W, Zhou Z, Zhang F, Hu K. Predictors of Distant Metastasis in Patients with Cervical Cancer Treated with Definitive Radiotherapy. J Cancer. 2019;10(17):3967-74.

Fagundes H, Perez CA, Grigsby PW, Lockett MA. Distant metastases after irradiation alone in carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys. 1992;24(2):197-204.

Williams NL, Werner TL, Jarboe EA, Gaffney DK. Adenocarcinoma of the cervix: should we treat it differently? Curr Oncol Rep. 2015;17(4):17.

Hildesheim A, Berrington de González A. Etiology and prevention of cervical adenocarcinomas. J Natl Cancer Inst. 2006;98(5):292-3.

Li H, Yang Y, Zhou H, Liu F, Li M, Chen L, et al. Clinicopathologic characteristics and survival analysis in stage IVB cervical cancer with hematogenous metastasis. Transl Cancer Res. 2019;8(4):1217-23.

Li H, Wu X, Cheng X. Advances in diagnosis and treatment of metastatic cervical cancer. J Gynecol Oncol. 2016;27(4):e43.

Zhou S, Peng F. Patterns of metastases in cervical cancer: a population-based study. Int J Clin Exp Pathol. 2020;13(7):1615-23.

Gardner AB, Charo LM, Mann AK, Kapp DS, Eskander RN, Chan JK. Ovarian, uterine, and cervical cancer patients with distant metastases at diagnosis: most common locations and outcomes. Clin Exp Metastasis. 2020;37(1):107-13.

Yu X, Wang Z, Zhang Z, Liu Y, Huang J. Postoperation of cervical cancer with intestine metastasis: a case report and literature review. World Journal of Surgical Oncology. 2016;14(1):2.

Bhandari V, Kausar M, Naik A, Batra M. Unusual Metastasis from Carcinoma Cervix. J Obstet Gynaecol India. 2016;66(5):358-62.

Singhal A, Masood S, Mahajan C, Hadi R, Bhalla S. Gastric and colonic metastasis from cancer cervix: An unusual progression with an uncommon cause of mortality. South Asian J Cancer. 2015;4(1):51-3.

National Cancer Center Network. Cervical Cancer (Version 1.2022)Oct 31, 2022. Available from:

Barlin JN, Kim JS, Barakat RR. Recurrent cervical cancer isolated to the sigmoid colon: A case report. Gynecol Oncol Case Rep. 2013;6:28-30.

Fukami T, Tsujioka H, Matsuoka S, Sorano S, Tohyama A, Yamamoto H, et al. Solitary transverse colon metastasis: A rare case of uterine cervical cancer recurrence. Eastern J Med. 2016;21(2):98-100.

Agrawal P, Gupta S, Saha S, Prestine A, Koladiya J, Dahiya V, et al. A case report: metastasis in ascending colon from carcinoma cervix. Int J Sci Res. 2017;6(7).

Full Text: PDF

Article Metrics

Abstract View : 70 times
PDF Download : 36 times

DOI: 10.24871/251202494-97


  • There are currently no refbacks.