Histopathological Spectrum of Gastrointestinal Polyps: A Retrospective Study at a Tertiary Care Hospital
), Shashikant Singh(2), Arvind Ahuja(3),
(1) Department of Pathology ,Bharat ratna late shri atal bihari vajpayee memorial medical college, Rajnandgaon, Chhattisgarh, 491441, India
(2) Consultant Pathologist, Dr. P. Bhasin Path labs, New Delhi-110048
(3) Professor Head of Department, Pathology, ABVIMS, Dr.RML Hospital, New Delhi,110001
Corresponding Author
Abstract
Background: Gastrointestinal polypoidal lesions are commonly encountered lesions on endoscopic examination. The histopathological examination categorises these lesions into neoplastic and non-neoplastic since these have the potential to get transformed into malignancy. This study aimed to assess the clinical profile as well as the histopathological spectrum of gastrointestinal polyps observed during endoscopic evaluation.
Methods: This study was a retrospective cross-sectional observational study conducted in the department of pathology at a tertiary care centre. All the histologically diagnosed gastrointestinal polypoidal lesions over a period of eight years were retrieved from the archives. Immunohistochemistry was applied as and when necessary. Univariate analysis was performed. Categorical variables were presented in number and percentage (%), and continuous variables were presented as mean. Appropriate descriptive statistics and graphical displays for different types of data have been presented.
Result: Two hundred cases of gastrointestinal tract polypoidal lesions were included. The age of the patients ranged from 8 months to 90 years. Juvenile rectal polyp was the most frequently encountered non-neoplastic lesion constituting 42.5 %( 85/200) and conventional adenoma was the commonest neoplastic lesion constituting 17.5 %(35/200) of cases. Most of the polypoidal lesions were less than 1 cm; however, in 6.5 %( 13/200) cases, it was larger than 1cm in size.
Conclusion: The gastrointestinal tract had a diverse range of non-neoplastic and neoplastic polyps. Histopathology is important in obtaining at a final diagnosis since it allows for a detailed investigation of occurrences and aids in distinguishing non-neoplastic disorders from those with clinical manifestations of malignancy.
Keywords: Gastrointestinal polyps, hyperplastic polyp, conventional adenoma
Keywords
References
Mills SE, Carter D, Greenson JK, Reuter VE, Stoler MH. Sternberg’s Diagnostic Surgical Pathology. Lippincott Williams & Wilkins; 2012.p.1543-68.
Kim EC, Lance P. Colorectal Polyps and their relationship to cancer. GastroenterolClin North Am 1997;26:1-14.
Chitturi R, Renuka I V, Latha P P, Vaishnavi R, Manasa B M. Morphologic spectrum of gastrointestinal polyps and polypoid lesions - A five year study. IP Arch CytolHistopathol Res 2018;3:151-55.
Arnold M, Abnet CC, Neale RE, Vignat J, Giovannucci EL, McGlynn KA et al. Global Burden of 5 Major Types of Gastrointestinal Cancer. Gastroenterology 2020;159:335-49.
Kulothungan V, SathishkumarK, LeburuS, Ramamoorthy T, Stephen S, Basavarajappa D et al. Burden of cancers in India - estimates of cancer crude incidence, YLLs, YLDs and DALYs for 2021 and 2025 based on National Cancer Registry Program. BMC Cancer 2022; 22:527.
Patil MV, Rathod U, Deshmukh M, Margam S, Kalgutkar AD. Spectrum of gastrointestinal polyps: A tertiary care hospital experience of five years. Indian J Pathol Oncol 2018;5:656-62.
Khajuria M, Bhardwaj S, Kumari R.A Study into the patterns of gastrointestinal tract polyps. JK Sci 2016;18:81-4.
Yoshizawa N, Yamaguchi H, Kaminishi M. Differential diagnosis of solitary gastric Peutz-Jeghers-type polyp with stomach cancer: a case report. Int J Surg Case Rep. 2018;51:261-264.
Sharma GL, Kumar LD, Debanth B, Akoijam NJ, Das P, Singh LR. Study of gastrointestinal endoscopic polypectomy specimens in rims hospital. J Evid Based Med Healthc 2018;5:1825-8.
Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68:394‑24.
Nutalapati V, Desai M, Thoguluva-Chandrasekar VS, Olyaee M, Rastogi A. Effect of dynamic position changes on adenoma detection rate during colonoscope withdrawal: systematic review and meta-analysis. Endosc Int Open. 2020:8:1842-49.
Zhu C, Wang Y, Zhang H, Yang Q, Zou Y et al. Morphology, Histopathology, and Anatomical Distribution of Sporadic Colorectal Polyps in Chinese Patients. Gastro Hep Advances 2023:2:964-70.
Gupta S, Lieberman D, Anderson J, Burke C, Dominitz J et al. Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer. Gastrointestinal Endoscopy 2020:91:463-85.
Sung JJY, Chiu H, Lieberman D, Kuipers E, Rutter M et al. Third Asia-Pacific consensus recommendations on colorectal cancer screening and postpolypectomy surveillance. Gut 2022;71:2152-66.
Xiaosheng He, Dong Hang, Kana Wu, Jennifer Nayor, David A et al. Long-term Risk of Colorectal Cancer After Removal of Conventional Adenomas and Serrated Polyps. Gastroenterology 2020:158:852-61.
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DOI: 10.24871/26120254-9
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