Comparison Between Evendo Score and Baveno VII Criteria for Predicting Esophageal Varices in Cirrhosis Patients
), Bachti Alisjahbana(2), Toni Baskoro(3),
(1) Division of Gastroentero-Hepatology, Department of Internal Medicine, Faculty of Medicine Universitas Padjajaran/Dr. Hasan Sadikin General Hospital, Bandung
(2) Division of Tropical Infectious Disease, Department of Internal Medicine, Faculty of Medicine Universitas Padjajaran/Dr. Hasan Sadikin General Hospital, Bandung
(3) Department of Internal Medicine, Faculty of Medicine Universitas Padjajaran/Dr. Hasan Sadikin General Hospital, Bandung
Corresponding Author
Abstract
Background: The EVendo score and Baveno VII criteria are non-invasive methods in predicting the presence of esophageal varices in patients with cirrhosis. The EVendo score is more practical to use in daily practice than the Baveno VII criteria because it does not require a liver stiffness measurement. This study aims to compare the performance of the EVendo score with the Baveno VII criteria for predicting the presence of esophageal varices in patients with liver cirrhosis.
Methods: This study was diagnostic study with cross-sectional approach on cirrhosis patients who had previously undergone upper gastrointestinal endoscopy who had laboratory examination data and liver stiffness measurement values. Based on the existing data, calculation and comparison of the diagnostic value of the EVendo score and the Baveno VII criteria were carried out. The research was conducted at dr. Hasan Sadikin based on patient data from April 2017 to May 2023.
Results: The Evendo score had a sensitivity of 80.5%, specificity 50%, PPV 84.6%, NPV 42.9%, positive likelihood ratio 1.61, and negative likelihood ratio 0.39. The Baveno VII criteria had a sensitivity of 95.1%, specificity of 25%, PPV 81.2%, NPV 42.9%, positive likelihood ratio 1.27, and negative likelihood ratio 0.2.
Conclusion: The results of this study show that the EVendo score and Baveno VII criteria have high sensitiviy but low specificity for predicting esophageal varices in patients with liver cirrhosis.
Keywords
References
Engelmann C, Clària J, Szabo G, Bosch J, Bernardi M. Pathophysiology of decompensated cirrhosis: Portal hypertension, circulatory dysfunction, inflammation, metabolism and mitochondrial dysfunction. Journal of hepatology. 2021;75:S49-S66.
Cheemerla S, Balakrishnan M. Global epidemiology of chronic liver disease. Clinical Liver Disease. 2021;17(5):365.
Enomoto H, Ueno Y, Hiasa Y, Nishikawa H, Hige S, Takikawa Y, et al. Transition in the etiology of liver cirrhosis in Japan: a nationwide survey. Journal of gastroenterology. 2020;55(3):353-62.
Sulaiman AS. The Prevalence and Clinical Predictors of Esophageal Varices in Liver Cirrhosis Patients at Dr. Cipto Mangunkusumo National Referral Hospital in Indonesia. Teikyo Medical Journal. 2022;45(04):6621-9.
Garcia-Tsao G, Sanyal AJ, Grace ND, Carey W. Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis. Hepatology. 2007;46(3):922-38.
Dong TS, Kalani A, Aby ES, Le L, Luu K, Hauer M, et al. Machine Learning-based Development and Validation of a Scoring System for Screening High-Risk Esophageal Varices. Clin Gastroenterol Hepatol. 2019;17(9):1894-901.e1.
de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C. Baveno VII - Renewing consensus in portal hypertension. J Hepatol. 2022;76(4):959-74.
Tabibian JH. EVendo Score for Esophageal Varices. 2021. p. https://www.mdcalc.com/calc/10175/evendo-score-esophageal-varices
Alswat K, Alanazi M, Bashmail A, Alkhamash M, Alqahtani SA, Al-Hamoudi W, et al. Validation of the EVendo score for the prediction of varices in cirrhotic patients. Saudi J Gastroenterol. 2022;28(5):378-84.
Jan M, Khan RTY, Ismail H, Shahzad S, Tasneem AA, Panezai MQ, et al. Utility of EVendo score as a screening tool for the detection of high risk esophageal varices in Pakistani population. Journal of Advances in Medicine and Medical Research. 2023;35(14):105-13.
Chittajallu P, Benhammou JN, Patel A, Dreskin B, Tabibian J, Dong T. S1205 Application of the EVendo Score for Variceal Screening in Patients with Hepatocellular Carcinoma. Official journal of the American College of Gastroenterology| ACG. 2021;116:S558.
Farkas Z, Kang D, Azeez S. S3406 EVendo Score: A Validation Study. Official journal of the American College of Gastroenterology| ACG. 2021;116:S1400.
Suk KT. Hepatic venous pressure gradient: clinical use in chronic liver disease. Clin Mol Hepatol. 2014;20(1):6-14.
Kamath PS, Wiesner RH, Malinchoc M, Kremers W, Therneau TM, Kosberg CL, et al. A model to predict survival in patients with end–stage liver disease. Hepatology. 2001;33(2):464-70.
Sterling RK, Lissen E, Clumeck N, Sola R, Correa MC, Montaner J, et al. Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology. 2006;43(6):1317-25.
Article Metrics
Abstract View
: 75 times
Download : 16 times
DOI: 10.24871/25320243-8
Refbacks
- There are currently no refbacks.
