Prevalence and Risk Factors of Functional Dyspepsia: A Population-Based Study
), Can Oner(2), Hüseyin Cetin(3), Engin Ersin Simsek(4),
(1) University of Health Sciences Kartal Dr Lutfi Kirdar City Hospital, Department of Family Medicine
(2) University of Health Sciences Kartal Dr Lutfi Kirdar City Hospital, Department of Family Medicine
(3) University of Health Sciences Kartal Dr Lutfi Kirdar City Hospital, Department of Family Medicine
(4) University of Health Sciences Kartal Dr Lutfi Kirdar City Hospital, Department of Family Medicine
Corresponding Author
Abstract
Background: Functional dyspepsia is one of the most common functional gastrointestinal disorders and affects more than 20% of the population. This study aimed to determine the prevalence of functional dyspepsia according to Rome IV criteria and its relation with social determinants.
Methods: This cross-sectional study was conducted in the Department of Family Medicine, Kartal Dr Lutfi Kırdar City Hospital Tuzla Training and Research Primary Health Care Center, Istanbul, Turkey from May - December 2019. The participants (aged 18-78) were selected using randomized sampling by a family physician according to the records. All participants underwent a clinical interview based on a questionnaire based on Rome IV criteria. The factors that were significant in the binary comparison were taken into logistic regression analysis (Backward: LR) to determine the causal relationship. P-values <0.05 were considered statistically significant.
Results: A total of 350 participants were enrolled to the study (43.4 %; n=152 male and 56.6%; n=198 female). The prevalence of functional dyspepsia was 16.9% (n=59). 62.7% (n=37) of dyspeptic patients had epigastric pain syndrome and 67.8% (n=40) of them had postprandial distress syndrome. Daily tee consumption, body mass index, and family history were found as social factors related to functional dyspepsia.
Conclusion: The prevalence of functional dyspepsia was 16.9% according to Rome IV criteria and most of the patients were female. Obesity was an important factor related to dyspepsia. Dyspeptic symptoms must investigate especially in obese female patients.
Keywords
References
Ford AC, Marwaha A, Sood R, Moayyedi P. Global prevalence of, and risk factors for, uninvestigated dyspepsia: a meta-analysis. Gut. 2015;64(7):1049-57.
Barberio B, Mahadeva S, Black CJ, Savarina EV, Ford AC. Systematic review and meta-analysis: global prevalence of uninvestigated dyspepsia according to the Rome criteria. Aliment Pharmacol Ther. 2020;52(2):1-12.
Talley NJ, Ford AC. Functional dyspepsia. N Engl J Med. 2015;373(19):1853-63.
Stanghellini V, Chan FK, Hasler WL, Malagelada JR, Suzuki H, Tack J, et al. Gastroduodenal disorders. Gastroenterology. 2016;150(6):1380-92.
Wei Z, Yang Y, Du T, Hao Y, Liu N, Gu Y, et al. Exercise is inversely associated with functional dyspepsia among a sample of Chinese male armed police recruits. BMC Gastroenterol. 2023;23(1):430. https://doi.org/10.1186/s12876-023-03072-z.
Caliskan H, Celik B, Ersoy S. Dispeptik yakınmalarlı acil servise müracaat eden hastalarda etiyolojik değerlendirme. Akademik Gastroenteroloji Dergisi. 2020;19(2):41-8.
Etcioglu E, Aydın A. Birinci Basamakta Dispepsi Şikayeti Olan Erişkin Hastaya Klinik Yaklaşım. Sakarya Tıp Dergisi. 2020;10:69-75.
Koksal AS, Dilek O, Ali Ö. Türkiye'de birinci basamak sağlık kurumlarına başvuran hastalarda dispepsi görülme sıklığı. Akademik Gastroenteroloji Dergisi. 2008;7(1):11-7.
Aziz I, Palsson OS, Törnblom H, Sperber AD, Whitehead WE, Simrén M. Epidemiology, clinical characteristics, and associations for symptom-based Rome IV functional dyspepsia in adults in the USA, Canada, and the UK: a cross-sectional population-based study. Lancet Gastroenterol Hepatol. 2018;3(4):252-62.
Kim ES, Kim N, Lee JY, Park KS, Shin JE, Nam K, et al. Prevalence and risk factors of functional dyspepsia in health check-up population: a nationwide multicenter prospective study. J Neurogastroenterol Motil. 2018;24(4):603-13.
Lee K, Kwon CI, Yeniova AÖ, Koyanagi A, Jacob L, Smith L, et al. Global prevalence of functional dyspepsia according to Rome criteria, 1990-2020: a systematic review and meta-analysis. Sci Rep. 2024;14(1):4172. https://doi.org/10.1038/s41598-024-54716-3.
Okumura T, Tanno S, Ohhira M, Tanno S. Prevalence of functional dyspepsia in an outpatient clinic with primary care physicians in Japan. J Gastroenterol. 2009;45(2):187-94. https://doi.org/10.1007/s00535-009-0168-x.
Aono S, Tomita T, Tozawa K, Morishita D, Nakai K, Okugawa T, et al. Epidemiology and clinical characteristics based on the Rome III and IV criteria of Japanese patients with functional dyspepsia. J Clin Med. 2022;11(9):2342. https://doi.org/10.3390/jcm11092342.
Ergül R, Dağlı Ü, Özmen E. Bolu İl Merkezi’nde gastroözofageal reflü hastalığı prevalansı: popülasyona dayalı çalışma. Turk J Gastroenterol. 2012;23(Suppl 1):SS-07.
Zagari RM, Law GR, Fuccio L, Cennamo V, Gilthorpe MS, Forman D, et al. Epidemiology of functional dyspepsia and subgroups in the Italian general population: an endoscopic study. Gastroenterology. 2010;138(4):1302-11. https://doi.org/10.1053/j.gastro.2009.12.057.
Aro P, Talley NJ, Ronkainen J, Storskrubb T, Vieth M, Johansson SE, et al. Anxiety is associated with uninvestigated and functional dyspepsia (Rome III criteria) in a Swedish population-based study. Gastroenterology. 2009;137(1):94-100. https://doi.org/10.1053/j.gastro.2009.03.039.
Matsuzaki J, Suzuki H, Asakura K, Fukushima Y, Inadomi JM, Takebayashi T, et al. Classification of functional dyspepsia based on concomitant bowel symptoms. Neurogastroenterol Motil. 2012;24(4):325-e164. https://doi.org/10.1111/j.1365-2982.2011.01859.x.
Le Pluart D, Sabaté JM, Bouchoucha M, Hercberg S, Benamouzig R, Julia C. Functional gastrointestinal disorders in 35,447 adults and their association with body mass index. Aliment Pharmacol Ther. 2015;41(8):758-67. https://doi.org/10.1111/apt.13143.
Duncanson KR, Talley NJ, Walker MM, Burrows TL. Food and functional dyspepsia: a systematic review. J Hum Nutr Diet. 2018;31(3):390-407. https://doi.org/10.1111/jhn.12506.
Huang ZP, Wang K, Duan YH, Yang G. Correlation between lifestyle and social factors in functional dyspepsia among college freshmen. J Int Med Res. 2020;48(8):0300060520939702. https://doi.org/10.1177/0300060520939702.
Kim YS, Choi SC. Socioeconomic disparities: a possible clue to a puzzle encompassing organic to functional gastrointestinal disorders. J Neurogastroenterol Motil. 2022;28(4):512-4. https://doi.org/10.5056/jnm22156.
Bangamwabo JB, Chetwood JD, Dusabejambo V, Ntirenganya C, Nuki G, Nkurunziza A, et al. Prevalence and sociodemographic determinants of dyspepsia in the general population
Article Metrics
Abstract View
: 88 times
Download : 23 times
DOI: 10.24871/25320249-15
Refbacks
- There are currently no refbacks.
