ERCP–PTBD Rendezvous Method in a Patient with Pancreatic Head Carcinoma and Duodenal Infiltration: A Case Report

Nikko Darnindro(1), Rabbinu Rangga Pribadi(2), Edi Mulyana(3),


(1) Departement of Gastroenterology, Fatmawati General Hospital
(2) Gastroenterology, Pancreatobilier and Digestive Endoscopy Division, Departement of Internal Medicine, Faculty of Medicine Universitas Indoensia, Cipto Mangunkusumo Hospital
(3) Departement of Gastroenterology, Fatmawati General Hospital
Corresponding Author

Abstract


Advanced pancreatic head cancer with tumor infiltration into the duodenum is capable of distorting the anatomy and is extremely challenging for selective biliary cannulation during ERCP. In these situations, the ERCP–PTBD rendezvous method served as a valuable alternative. Therefore, this case report aimed to describe the case of a 75-year-old man who presented with obstructive jaundice. On examination, the patient was tachycardic and febrile (38.0°C), with pale conjunctivae and marked scleral icterus. A palpable mass was observed in the epigastric region, and laboratory evaluation showed a total bilirubin level of 18.64 mg/dL. Furthermore, MRCP showed a mass in the pancreatic head infiltrating the duodenum, leading to significant intra- and extrahepatic biliary dilatation. The patient was initially subjected to transhepatic biliary drainage (PTBD), followed by an ERCP using the rendezvous method due to the tumor-related distortion of the papilla. During this procedure, a guidewire was advanced through the PTBD tract and navigated under fluoroscopy into the duodenum, facilitating biliary access and successful placement of a biliary stent. Two days after the intervention, the condition improved, with bilirubin decreasing to 8.91 mg/dL, and the patient was subsequently discharged in stable condition. This case showed the rendezvous method as an effective alternative biliary drainage strategy for patients in whom conventional ERCP was hindered by tumor-related anatomical alterations.

Keywords


ERCP, PTBD, Rendezvous, Pancreatic Head Cancer, Obstructive Jaundice

References


National Cancer Institute Surveillance E and ERP. Cancer Stat Facts: Pancreatic Cancer [Internet]. [cited 2025 Aug 17]. Available from: seer.cancer.gov

Ranganath R, Chu Q. Global trends in pancreatic cancer among the Asia-Pacific population. Vol. 12, Journal of Gastrointestinal Oncology. AME Publishing Company; 2021. p. S374–86.

Pawa S, Marya NB, Thiruvengadam NR, Ngamruengphong S, Baron TH, Bun Teoh AY, et al. American Society for Gastrointestinal Endoscopy guideline on the role of therapeutic EUS in the management of biliary tract disorders: summary and recommendations. Gastrointest Endosc. 2024 Dec 1;100(6):967–79.

Yousaf MN, Ehsan H, Wahab A, Muneeb A, Chaudhary FS, Williams R, et al. Endoscopic retrograde cholangiopancreatography guided interventions in the management of pancreatic cancer. World J Gastrointest Endosc. 2020 Oct 16;12(10):323–40.

Niemelä J, Kallio R, Ohtonen P, Saarnio J, Syrjälä H. Impact of cholangitis on survival of patients with malignant biliary obstruction treated with percutaneous transhepatic biliary drainage. BMC Gastroenterol. 2023 Dec 1;23(1).

Singh I, Chou JF, Capanu M, Park J, Yu KH, Varghese AM, et al. Morbidity and mortality in patients with stage IV pancreatic adenocarcinoma and acute cholangitis: Outcomes and risk prognostication. Pancreatology. 2024 Jun 1;24(4):608–15.

Valente R, Coppola A, Scandavini CM, Arnelo U. Endoscopic workup in pancreatic cancer. Vol. 110, International Journal of Surgery. Wolters Kluwer Health Inc; 2024. p. 6064–9.

Adiwinata R, Livina A, Waleleng BJ, Tendean N, Gosal F, Rotty L, et al. Palliative Management of Advanced Pancreatic Cancer: The Role of Gastroentero-hepatologist. Vol. 52, Acta Med Indones-Indones J Intern Med. 2020.

Masood M, Irani S, Fotoohi M, Wancata L, Krishnamoorthi R, Kozarek RA. The Palliation of Unresectable Pancreatic Cancer: Evolution from Surgery to Minimally Invasive Modalities. Vol. 14, Journal of Clinical Medicine. Multidisciplinary Digital Publishing Institute (MDPI); 2025.

Pfau PR, Pleskow DK, Banerjee S, Barth BA, Bhat YM, Desilets DJ, et al. Pancreatic and biliary stents. Gastrointest Endosc. 2013 Mar;77(3):319–27.

Tavakkoli A, Elmunzer BJ, Waljee AK, Murphy CC, Pruitt SL, Zhu H, et al. Survival analysis among unresectable pancreatic adenocarcinoma patients undergoing endoscopic or percutaneous interventions. Gastrointest Endosc. 2021 Jan;93(1):154-162.e5.

Hsu YC, Lee HY, Chang CM, Lin CY, Liu YS, Huang HS. Clinical outcomes of percutaneous transhepatic biliary drainage at different Couinaud’s hepatic entry segments for treating obstructive jaundice. Front Surg. 2023 Jan 24;10.

Doyle JB, Sethi A. Endoscopic Ultrasound-Guided Biliary Drainage. Vol. 12, Journal of Clinical Medicine. Multidisciplinary Digital Publishing Institute (MDPI); 2023.

Itonaga M, Kitano M. Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer. Vol. 58, Clinical Endoscopy. Korean Society of Gastrointestinal Endoscopy; 2025. p. 40–52.

Zafar Y, Azam H, Azhar MA Bin, Shaheen F, Javaid SS, Manzoor L, et al. Efficacy of endoscopic ultrasound-guided biliary drainage of malignant biliary obstruction: a systematic review and meta-analysis of randomized controlled trials. Vol. 58, Clinical Endoscopy. Korean Society of Gastrointestinal Endoscopy; 2025. p. 533–43.

Yang MJ, Kim JH, Hwang JC, Yoo BM, Kim SS, Lim SG, et al. Usefulness of combined percutaneous-endoscopic rendezvous techniques after failed therapeutic endoscopic retrograde cholangiography in the era of endoscopic ultrasound-guided rendezvous. Medicine (United States). 2017 Dec 1;96(48).

Liu Y Di, Wang ZQ, Wang D, Yang YS, Linghu Q, Wang WF, et al. Stent implantation through the rendezvous technique of PTBD and ERCP: The treatment of obstructive jaundice. J Dig Dis. 2007;8:192–202. doi: 10.1111/j.1443-9573.2007.00305.x


Full Text: PDF

Article Metrics

Abstract View : 15 times
PDF Download : 7 times

DOI: 10.24871/2712026101-106

Refbacks

  • There are currently no refbacks.